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KMID : 0378019800230050057
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New Medical Journal
1980 Volume.23 No. 5 p.57 ~ p.65
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Bacterial Culture and Antibiotics Sensitivity Test of Postoperative Wound Infection & Result of Clinical Trial of Cefuroxime
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Abstract
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Wound infection has been a major problem for surgeon despite the vigorous efforts to prevent wound infection.
Early in 1950s as many as 80% of postoperative wound infection were caused by Staphylococcus aureus.
Now wound infection caused by staphylococcus decreased while infection due to gram negative organisms increased and many reports indicating the important role of anaerobic organisms in many surgical infections.
Bacterial cultures and antibiotic sensitivity tests were performed on 52 cases of postoperative wound infection during March 1979 to December 1979 at Seoul National University Hospital.
The bacterial cultures from 52 cases of postoperative wound infection are consisted of 11 cases of negative culture,
9 cases of single organism and 32 cases of mixed organisms.
93 organisms were isolated from 41 cases of positive culture.
The bacterial strains are consist of 20 cases (21.5%) of gram positive strains and 73 cases (78.50) of gram negative strains.
E. coli was the most common pathogen (34.0/6) and next common is Staphylococcus
aureus (10.8%) Klebsiella (9.7%) Pseudomonas (9.70) Bacteroides (7.5%) Enterobacter
(6.50) Proteus (5.4%) Clostridium (5.40) Streptococcus (3.2%) Enterococcus (2. 1% ) In antibiotics sensivity test
8.6% of organisms are resistant to all antibitics
46.2% of organisms are sensitive to Cefuroxime
45.1% to Gentamycin
40.9 o to Cephalothin
36.9% to Chloramphenicol
31.2% to Kanamycin
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KEYWORD
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